Polypeptide drugs have developed rapidly due to their advantages of strong tumor penetration, low immunogenicity and high biological activity. PDC drugs integrate the advantages of polypeptide drugs, is another type of drug based on polypeptide, by pointing to the Peptide and the intermediate linker and linking the drug to target the target, which is specifically divided into three parts: Homing Peptide, Linker and Payload. With small molecular weight and high hydrophilicity, PDC is easy to be quickly excreted through the kidney, which helps to improve the safety of the drug. Meanwhile, PDC has the advantages of stronger tumor penetration, low immunogenicity and low production cost. At present, many manufacturers focus on the fields of peptide coupled small molecule drugs, peptide coupled nucleic acids, peptide coupled radionuclides and so on. Our company can provide related peptide coupling services according to customer needs.

Polypeptide conjugated small molecules

Using our peptide and organic small molecule synthesis platform, we provide peptide coupling small molecule services for the majority of pharmaceutical companies (Big Pharma, biotech, etc.).

Polypeptide-coupled nucleic acids

At present, the development of small nucleic acid drugs has been hampered by the delivery system. The nucleic acid drug delivery technology used in the market can not solve the problem of targeting specific tissues, and peptides as a targeted drug delivery system is another approach, which can solve many problems that other delivery systems can not solve. Because of the characteristics of high uptake rate and high endosome escape rate of polypeptide-coupled nucleic acids, polypeptide-coupled nucleic acid drugs are also a hot research field in recent years.

Using our production platform of polypeptide and PMO monomer and PNA monomer, we provide peptide coupling small nucleic acid services for the majority of pharmaceutical companies (Big Pharma, biotech, etc.). The main purpose is to promote the smooth development of peptide nucleic acid research at home and abroad, and provide an easy to obtain peptide nucleic acid resources, technology and research platform for researchers.

Polypeptide coupled nuclides

Radionuclides are atoms with too much energy, which can spontaneously emit particles or rays, and the energy released can achieve the purpose of diagnosis or treatment, but the shortcomings of radionuclides such as low stability, uncontrollability, and non-target site toxicity limit their application in medicine. After chelating radionuclides as payloads and chelators, they are coupled with peptides through linkers to form polypeptide-coupled radionuclides, guiding the precise targeting of radionuclides, and combining the advantages of peptides such as better tissue penetration and lower immunogenicity. It can achieve the ideal drug delivery in the body, achieve the role of reducing toxicity and increasing efficacy.

At present, the application direction of polypeptide-coupled nuclides is therapeutic and diagnostic imaging. We can provide peptide coupling radionuclide services for the majority of pharmaceutical companies (Big Pharma, biotech, etc.) by using our peptide and macrocyclic bifonuclear (DOTA,NOTA, etc.) production platform.Pharma，biotech）

Delivery standard

General delivery products are freeze-dried powder, providing products HPLC, MS.Quality inspection report.

* If you have other testing requirements, please contact us in advance.